Prebiotics

AOXcare: A Microbiome-First Solution for Implant Maintenance

AOXcare is a next-generation oral care product designed to support patients with full-arch implant restorations, including All-on-X prostheses. Created by Dr. Emily Stein, PhD (Primal Health), and Dr. Tom Larkin, DDS (Proactive Oral Wellness), AOXcare leverages Protektin™, a proprietary prebiotic compound that shifts the oral microbiome toward homeostasis, without disrupting beneficial flora.

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The Challenge: Dysbiosis Beneath Full-Arch Prostheses

The intaglio surface of screw-retained implant restorations presents a nearly impossible environment for patients to manage at home. Biofilm accumulates in these hard-to-access areas, often without symptoms, until inflammation or infection emerges.

Studies suggest that 40–60% of implant failures are related to dysbiosis-driven peri-implantitis. While mechanical biofilm disruption is critical, it often isn’t enough.

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The AOXcare Mechanism: Microbial Metabolism Modulation

Protektin, the active ingredient in AOXcare, is a plant-based prebiotic compound developed by Dr. Stein through years of microbiome research. It doesn’t kill bacteria—it alters their behavior. Specifically, Protektin:

• Suppresses acid production by dysbiotic oral bacteria

• Feeds beneficial commensals that are associated with homeostasis

• Reduces pathogenic virulence factors like proteases and biofilm adhesins

• Helps restore a more resilient microbial community around implants

This represents a shift from antiseptic thinking to microbiome engineering, aligning with emerging science in periodontal and peri-implant care.

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Clinical Applications

AOXcare is recommended as an adjunctive therapy for:

• All-on-X and other full-arch implant restorations

• Maintenance-phase patients with a history of mucositis or peri-implantitis

• Post-treatment biofilm suppression following debridement, laser, or GBT

• Patients resistant to traditional antimicrobials or concerned about overuse of chlorhexidine and alcohol-based rinses

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Integration Into Your Protocol

AOXcare can be dispensed directly from your office or recommended for daily home use. We suggest:

• Dispensing during hygiene re-care appointments

• Integrating into implant maintenance programs

• Including in phase-contrast microscopy or salivary diagnostics protocols

• Reinforcing as part of your practice’s oral-systemic health model

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Why AOXcare?

Prebiotic—not antimicrobial
Easy for patients to use
Rooted in microbiome science
Designed by a PhD microbiologist and a dentist focused on prevention
Ideal for biologically minded practices

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Backed by Science. Built for Dentistry

AOXcare represents a paradigm shift in oral care: not killing bacteria, but cultivating health. Empower your patients to protect their investment—and their systemic health—with a novel approach to implant maintenance.

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