
Ozone Water
Ozonated water is increasingly being used in dentistry as a natural antimicrobial agent to help treat and prevent dental infections, particularly in periodontal and peri-implant diseases. Ozone (O₃), a triatomic form of oxygen, has strong oxidative properties that make it highly effective against bacteria, viruses, fungi, and protozoa without the risk of developing resistance, unlike antibiotics.
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How Ozonated Water Works
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When ozone gas is dissolved in water, it creates ozonated water, which maintains ozone’s antimicrobial properties in a safe, biocompatible liquid form.
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Upon contact, ozone oxidizes the cell walls of microorganisms, leading to rapid cell lysis and death.
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Ozonated water also increases local oxygen availability, which helps support tissue healing and regeneration.
Clinical Applications in Dentistry
1. Periodontal Therapy
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Used as an irrigant during scaling and root planing.
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Effectively reduces the microbial load in deep periodontal pockets, including anaerobic bacteria like Porphyromonas gingivalis and Treponema denticola.
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Promotes faster healing of gingival tissues and reduces inflammation.
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2. Peri-implant Mucositis & Peri-implantitis
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Ozonated water can be used to irrigate peri-implant sulci.
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Helps decontaminate the implant surface and surrounding tissues without harming the titanium surface or soft tissues.
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May support re-osseointegration in early peri-implantitis when used as part of a comprehensive protocol.​​
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​3. Endodontic Treatment
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Serves as an irrigant in root canal therapy, especially as an adjunct to traditional agents like sodium hypochlorite.
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Penetrates dentinal tubules and eliminates resistant microorganisms such as Enterococcus faecalis.
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4. Surgical Applications
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Used to rinse extraction sites, implant placements, and post-operative areas.
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Reduces the risk of dry sockets, infection, and promotes hemostasis and faster healing.
Advantages of Ozonated Water in Dental Care
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Broad-spectrum antimicrobial without toxicity to human cells at therapeutic concentrations.
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Non-allergenic and non-mutagenic.
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Improves tissue oxygenation, enhancing the healing response.
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Leaves no residue or resistance, unlike chemical antiseptics or antibiotics.
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Limitations and Considerations
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Ozone is unstable and must be generated chairside immediately before use.
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Requires specialized equipment, such as an ozone generator.
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Proper training is essential for safe and effective use.